Mechanisms of antibody mediated rejection and accommodation. We use genetically modified transplant models of kidney and cardiac transplantation.
Pulsatile Renal Preservation: Long term pulsatile preservation with novel perfusates will be tested in large animal and human discard organ models.
A normothermic oxygenated reperfusion model will allow histologic and functional evaluation of kidneys receiving novel perfusates or other protective agents in preservation injury