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| Confluent |
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| Monolayer |
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| Starvation |
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Stable post-translationaly modified MTs shown in green, MTOC shown in red.
Fibroblasts are grown until they form a confluent monolayer then serum
starved for two days. Serum-starved cells are unable to polarize their
cytoskeleton in response to wounding. Addition of serum triggers polarization
of the microtubules in two ways: stable MTs are formed and oriented towards
the wound edge, and the MTOC is reoriented so that it lies between the
nucleus and the wound edge.
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