Publications

Gundersen, G.G. 2002. Evolutionary Conservation of Microtubule Capture Mechanisms. Nature Rev. Mol. Cell Biol., In Press.
Yoon, J.T., Palazzo, A.F., Delohrey, T.M., Warburton, P. E., Bruce, J.N., Gundersen, G.G. & Weinstein, I.B. 2002. CP248, a derivative of sulindac sulfone induces mitotic arrest and growth inhibition in glioblastoma cells by depolymerizing microtubules. (submited)
Lin, S.X., Gundersen, G.G. & Maxfield, F.R. 2002. Exit from the endocytic recycling compartment to cell surface depends on stable, detyrosinated (Glu) microtubules and kinesin.Mol. Biol. Cell 13: 96-109.
Palazzo, A.F., Joseph, H. L., Chen, Y.-J., Alberts, A. S., Pfister, K. K., Dujardin, D. L., Vallee, R. B. & Gundersen, G. G. 2001. CDC42, dynein and dynactin regulate MTOC reorientation independent of Rho regulated microtubule stabilization.Curr. Biol. 11:1536-1541.
Palazzo AF, Cook TA, Alberts AS, Gundersen GG. 2001. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat Cell Biol. 2001 Aug;3(8):723-9.
Vu TH, Hays AP, Tanji K, Younger D, Gundersen GG, Eastwood A, Braun CW, DiMauro S, Bonilla E. 2001. Myopathy with tubulin-reactive crystalline inclusions. Neurology. Jul 10;57(1):149-52.
Infante AS, Stein MS, Zhai Y, Borisy GG, Gundersen GG. 2000. Detyrosinated (Glu) microtubules are stabilized by an ATP-sensitive plus-end cap. J Cell Sci. Nov;113 (Pt 22):3907-19.
Liao, G., Kreitzer, G., Cook, T.A., and Gundersen, G.G. 1999. A signal transduction pathway involved in microtubule-mediated cell polarization. FASEB J. 13: S257-S260.
Smilenov, L., Mikhailov, A., Pelham, R.L., Marcantonio, E.E. and Gundersen, G.G 1999. Focal adhesion motility revealed in stationary fibroblasts. Science 286: 1041-1244.
Martys, J. L., Mikhailov, A., Ho, C.-L., Liem, R.K.H., and Gundersen, G.G. 1999. Intermediate filaments in motion: Observations of intermediate filaments in cells using green fluorescent protein-vimentin. Mol. Biol. Cell 10: 1289-1295.
Kreitzer, G., Liao, G.L. & Gundersen, G.G. 1999. Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism. Mol. Biol. Cell 10: 1105-1118.
Gundersen, G.G. and Cook, T.A. 1999. Microtubules and Signal Transduction. Curr. Opin. Cell Biology 11: 81-94.
Mikhailov, A. and Gundersen, G.G. 1998. Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxol. Cell Motility.Cytoskel. 41: 325-340.
Liao, H., Li, Y., Brautigan, D.L., and Gundersen, G.G. 1998. Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein tau. J. Biol. Chem. 273: 21901-21908.
Gundersen, G.G., Gurland, G., Cook, T.A. and Liao, G.L. 1998. Microtubules as determinants of cellular polarity. Biol. Bull. 194: 358-360.
Ho, C.-L., Martys, J. L., Mikhailov, A., Gundersen, G.G. and Liem, R.K.H. 1998. Novel features of intermediate filament dynamics revealed by green fluorescent protein fusion proteins. J. Cell Sci. 111: 1767- 1778.
Liao, G. and Gundersen, G.G. 1998. Kinesin is a candidate for crossbridging microtubules and intermediate filaments: selective binding of kinesin to detyrosinated tubulin and vimentin. J. Biol. Chem. 273: 9797-9803.
Cook, T.A., Nagasaki, T. and Gundersen, G.G. 1998. Rho GTPase mediates the selective stabilization of microtubules in vivo. J. Cell Biol. 141: 175-185.
Nagasaki, T. and Gundersen, G.G. 1996. Depletion of lysophosphatidic acid triggers a loss of oriented detyrosinated microtubules in motlie fibroblasts. J. Cell Sci. 109: 2461-2469.
Kessin, R.H., Gundersen, G.G., Zaydfudim, V., Grimson, M., Blanton, R.L. 1996 How cellular slime molds evade nematodes. Proc. Natl. Acad. Sci. 93: 4857-4861.
Liao, G., Nagasaki, T. and Gundersen, G.G. 1995. Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting MT level: Implications for the role of dynamic microtubules in cell locomotion. J. Cell Sci. 108: 3473-3483.
Gurland, G. and Gundersen, G.G. 1995. Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts. J. Cell Biol. 131: 1275-1290.
Mikhailov, A. and Gundersen, G.G. 1995. Centripetal transport of microtubules in motile cells. Cell Motil. Cytoskel. 32: 173-186.
Nagasaki, T., Liao, G. and Gundersen, G.G. 1994. Isolated plasma membranes induce the loss of detyrosinated microtubules and other contact inhibition-like responses in migrating NRK cells. J. Cell Sci. 107: 3413-3423.
Gundersen, G.G., Kim, I. and Chapin, C.J. 1994. Induction of stable microtubules in 3T3 fibroblasts by TGF-beta and serum. J. Cell Sci. 107: 645-659.
Gurland, G. and Gundersen, G.G. 1993. Protein phosphatase inhibitors induce the selective breakdown of stable microtubules in fibroblasts and epithelial cells. Proc. Natl. Acad. Sci (USA) 90: 8827-8831.
Nagasaki, T., Chapin, C.J. and Gundersen, G.G. 1992. Distribution of detyrosinated microtubules in motile NRK fibroblasts is rapidly altered upon cell-cell contact: Implications for contact inhibition of locomotion. Cell Motility Cytoskel. 23: 45-60.
Chapin, S.J., Bulinski, J.C. and Gundersen, G.G. 1991. Microtubule bundling in cells. Nature 349: 24.
Bulinski, J.C. and Gundersen, G.G. 1991. Stabilization and post-translational modification of microtubules during cellular morphogenesis. Bioessays 13: 285-293.
Gundersen, G.G., Khawaja, S. and Bulinski, J.C. 1989. Generation of a stable, post- translationally modified microtubule array is an early event in myogenic differentiation. J. Cell Biol. 109: 2275-2288.
Gundersen, G.G. and Bulinski, J.C. 1988. Selective stabilization of microtubules oriented toward the direction of cell migration. Proc. Natl. Acad. Sci. (USA) 85: 5946-5950.
Khawaja, S., Gundersen, G.G. and Bulinski, J.C. 1988. Enhanced stability of microtubules enriched in detyrosinated tubulin is not a function of detyrosination level. J. Cell Biol. 106: 141-149.
Gundersen, G.G., Khawaja, S. and Bulinski, J.C. 1987. Microtubules enriched in detyrosinated tubulin in vivo are less dynamic than those enriched in tyrosinated tubulin. In The Cytoskeleton In Cell Differentiation and Development, J. Arechaga and R. Maccioni, eds. IRL Press, Oxford. pp. 75-81.
Bulinski, J.C., Gundersen, G.G. and Webster, D.R. 1987. A function for tubulin tyrosination? Nature 328: 676.
Webster, D.R., Gundersen, G.G., Bulinski, J.C. and Borisy, G.G. 1987. Differential turnover of tyrosinated and detyrosinated microtubules. Proc. Natl. Acad. Sci. (USA) 84: 9040-9044.
Webster, D.R., Gundersen, G.G., Bulinski, J.C. and Borisy, G.G. 1987. Assembly and turnover of detyrosinated alpha tubulin in vivo. J. Cell Biol. 105: 265-276.
Gundersen, G.G., Khawaja, S. and Bulinski, J.C. 1987. Post-polymerization detyrosination of alpha tubulin: a mechanism for subcellular differentiation of microtubules. J. Cell Biol. 105: 251-264.
Bulinski, J.C. and Gundersen, G.G. 1986. Preparation of antibodies reactive with specific regions of cytoskeletal proteins. Methods Enzymol 134: 453-460.
Gundersen, G.G. and Bulinski, J.C. 1986. Microtubule arrays in differentiated cells contain elevated levels of a post-translationally modified form of tubulin. Eur. J. Cell Biol. 42: 288-294.
Geuens, G., Gundersen, G.G., Nuydens, R., Cornelissen, F., Bulinski, J.C. and De Brabander, M. 1986. Ultrastructural colocalization of tyrosinated and detyrosinated alpha tubulin in interphase and mitotic cells. J. Cell Biol. 103: 1883-1893.
Gundersen, G.G. and Bulinski, J.C. 1986. Distribution of tyrosinated and nontyrosinated alpha tubulin in the mitotic spindle. J. Cell Biol. 102: 1118-1126.
Gundersen, G.G., Kalnoski, M.H. and Bulinski, J.C. 1984. Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo. Cell 38: 779-789.