... Courses are listed alphabetically.
Biochemistry and Molecular Biology I, II
The course Web page can be found at Courseworks
- Course number: G6300X, G6301Y
- Offered: Fall & Spring, each year.
- Instructors:Richard Mann and Stephen P. Goff
- Prerequisite: College Biochemistry, Biology and Chemistry
- Content:This course is for all first year Ph.D. students and provides them with a unified curriculum that covers many of the topics that students need to know to successfully carry out research in biological sciences. The topics include basic biochemical principles, processes common to all eukaryotic cells such as transcription, translation and the cell cycle, and mechanisims of cell-cell signaling.
- 4.5 points per semester
Biochemistry of Nucleic and Protein Synthesis.
- Course number: G4026Y
- Offered: Spring, each year.
- Instructor:
P.R. Srinivasan
- Prerequisite: A basic course in biochemistry or
biology or permission of the instructor.
- Content: Structure and
organization of chromatin, nucleic acid hybridization and sequence
complexity of DNA, DNA and RNA
sequencing methods, current views of replication and repair,
transcription and translation, regulation of nucleic
acid and protein synthesis, recombinant DNA techniques, gene transfer,
and gene duplication. Discussion of
original papers and evaluation of experimental procedures and
conclusions. Lectures preceded by an hour-long
optional conference. (Given at the Morningside Campus.)
- 3 points
Diffraction Analysis of Macromolecules.
- Course number: G6275Y
- Offered: Spring, Odd numbered years
- Instructor:
W. Hendrickson
- Prerequisite: Biophysical Chemistry G4170 or the
instructors’ permission.
- Content: Diffraction theory and applications to
protein, nucleic acid, and membrane structures. Topics include electron
microscopy, x-ray diffraction, protein
crystallography, electron and neutron diffraction and electron
microscopy.
- 4.5 points
General Biochemistry
- Course number: G4021X
- Offered:Fall, Each year.
- Instructor: Alvin
I. Krasna
- (Primarily for students in departments other than biochemistry).
- Prerequisite: General and organic chemistry.
- Content: An integration, from a dynamic point of
view, of cellular
constituents with the chemical processes of living systems: chemistry and
function, mode of synthesis and
degradation by the cell, the characterization and role of particular
enzymes and coenzymes in these reactions,
and the mechanisms of oxidation and energy production. Nucleic acids,
replication, and the genetic code. (Given
at the Morningside campus.)
- 3 points
Membrane Receptors and Transport Proteins.
- Course number: G6045Y
- Offered: Spring, Odd numbered years.
- Instructor:
A. Karlin
- Prerequisites: Biochemistry and Molecular Biology of Eukaryotes I (G6300X);
Molecular Biophysics (G4250).
- Content: Molecular structure and
function of membrane proteins; general principles and common threads.
- 3 points
- Course number: G4250X
- Offered: Fall, each year
- Instructors:
B. Honig and Staff.
- Prerequisite: Basic physical and organic chemistry
and the instructor’s permission.
- Content: Primarily intended to satisfy
the requirements of graduate students. Methods and principles
involved in studying the structure and function of
proteins, nucleic acids, membranes and their macromolecular assemblies.
Noncovalent forces and
conformational analysis; ultracentrifugation, viscometry, circular
dichroism, fluorescence, magnetic resonance,
conformational changes in proteins and nucleic acids, topological
properties of macromolecules.
- 4.5 points
- Course number: G6270Y
- Offered: Spring, Even numbered years.
- Instructor:
A. G. Palmer
- Prerequisite: the instructor’s permission or
Biophysical chemistry G4170.
- Content: Theoretical principles and applications of
NMR spectroscopy for the study of biological macromolecules, including
proteins, nucleic acids and
carbohydrates, in solution.
- 4 points
Research in Biochemistry.
- Course number: G9015X(Fall)-G9016Y(Spring)
- Offered: Each year.
- Instructors: Staff.
- Prerequisite: Instructor’s permission.
- 2 to 10 points
Special Methods of Biochemistry.
- Course number: G6011X(Fall)-G6012Y(Spring)
- Offered: Each year.
- Instructor: Staff.
- Prerequisite: Permission of the department.
- Content: Practical experience in the use of
biochemical methods, with the
aim of preparing the student for research.
- 2 to 10 pts.
Structure and Function of Nucleic Acids.
- Course number: G4024Y
- Offered: Spring, Even numbered years.
- Instructor:
Staff
- Prerequisite: Organic chemistry.
- Content: The structure, dynamics, catalytic
reactivity and biological function of DNA,
RNA, and their derivatives.
- 4 points
Table of Contents | Major areas of research
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