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Iva Greenwald’s lab uses the nematode, Caenorhabditis elegans, to study how cells communicate with each other to specify fate determination during development and Richard Mann’s lab studies how homeodomain-c ontaining transcription factors control developmental pathways in the fruit fly, Drosophila melanogaster. Richard Axel’s lab is dissecting the development of the mammalian olfactory neurons, in particular characterizing the role of the odorant receptor proteins and deciphering the specificity of neuronal connectivity. Thomas Jessell’s lab studies the development of the vertebrate spinal cord and has identified key molecular events that confer identity to cells. Finally, mouse gene knock-out technology is being used by Steve Goff’s lab to provide insights into the roles of various signal transduction molecules in vertebrate development. Lab Web Sites Iva Greenwald Thomas Jessell Richard Mann