Click on image to enlarge and learn more about this topic. Richard Axel’s lab is characterizing how individual olfactory neurons choose to express only one among thousands of odorant receptor genes. Kathryn Calame’s lab studies gene expression in the immune system, in particular the regulation of the IgH and c-myc genes. The Hirsh lab studies signalling events that regulate the inflammatory response. In addition to his studies of retroviral replication, Steve Goff is exploring the molecular behavior of viral oncogenes and their role in signal transduction. Richard Mann’s lab studies post-transcriptional mechanisms that control activity and specificity of homeodomain-containing transcription factors. The Gottesman lab studies the control of transcription termination in bacteriophage by RNA binding proteins as well as the control of gene expression in thyroid cells. Lab Web Sites Richard Mann