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Wayne Hendrickson develops new diffraction methods and uses them to solve structures of proteins involved in signal transduction, viral activity and many other processes. Using crystallographic techniques,Arthur Palmer uses NMR to study the macromolecular structure of proteins and RNA. Arthur Karlin studies membrane receptors and transport proteins by combining mutagenesis and site-directed reactions. Lawrence Shapiro uses structural information obtained from X-ray crystallography to direct biochemical studies of biological problems, particularly involving neuronal cell adhesion and neural patterning. Lab Web Sites Wayne Hendrickson Arthur Palmer Lawrence Shapiro

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