The Neurological Institute of New York Columbia University Medical Center Department of Neurology
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Neuroscience Research at Columbia

STROKE AND CRITICAL CARE



The Stroke Center
The Northern Manhattan Study (NOMAS) and the Northern Manhattan Family Study

Clinical Research Programs

Randolph S. Marshall, Division Head


Behavioral and physiologic investigation of early hemispheric ischemia in patients undergoing therapeutic carotid balloon test occlusions. Evaluation of visual-spatial dysfunction using behavioral and functional imaging methodologies.

Jay P. Mohr


Research is focused on clinical, radiologic and pathologic correlations of clinical stroke syndromes; doppler studies and cerebral hemodynamics of large-artery disease; arteriovenous malformations (AVMs); studies of the course and outcome of stroke and its various subtypes; cardiac and hematologic risk factors of stroke; and modification of stroke outcome by specific therapies tested in multi-center trials.

Mitchell S. Elkind


Stroke risk factors and prevention. Focus on different inflammatory markers and infections, such as C. pneumoniae and periodontal disease, as potential causes of atherosclerosis and ischemic stroke. Use of high-resolution duplex doppler ultrasonography as a measure of stroke risk. Clinical trials of neuroprotectants and surgical hemicraniectomy for acute stroke, and antiplatelet and of other therapies for stroke prevention.

Bernadette Boden-Albala


Research focuses on stroke and cardiovascular disease with emphasis on health disparities among gender and race-ethnic groups, and the social dimensions of stroke. Design of community-based stroke prevention program, and social support group.

John W. Krakauer


The Motor Performance Laboratory
The Motor Performance Laboratory is a research facility dedicated to the study of the neural basis of limb movement control in health and neurologic disease.

Cerebral Localization Laboratory

Ronald M. Lazar, Randolph S. Marshall


A clinical research unit dedicated to investigation of the behavioral outcomes of strokes and related vascular diseases. Computerized assessment of stroke patients' behaviors, functional magnetic resonance imaging, superselective arterial amobarbital (Wada) testing, and transcranial doppler ultrasonography allow measurement of cerebral plasticity with the principal focus on the brain's abilities to compensate for injury.

Joanne R. Festa


Research focuses on the neurocognitive outcomes of stroke and related vascular diseases such as heart failure, carotid disease, and AVMs. Design and conduct neurocognitive outcomes research in multi-center clinical trials.

Basic Research Laboratory

E. Sander Connolly, Augusto Parra


Mechanisms of ischemic injury. Cellular and molecular neuroprotective mechanisms and new therapeutic strategies

CRITICAL CARE


Neurological Intensive Care

Stephan A. Mayer, Director


Investigations of the effects of intracerebral and subarachnoid hemorrhage on cerebral blood flow, intracranial pressure, and the cardiovascular system; and studies of cognitive dysfunction and quality of life after subarachnoid hemorrhage.

Augusto Parra


Clinical trials and outcomes research related to intracerebral and aneurysmal subarachnoid hemorrhage. Clinical trials of hypothermia and hemicraniectomy for acute ischemic stroke. Quality of life and cognitive function after aneurysmal subarachnoid hemorrhage. Other research interests include neurogenic cardiac arrhythmias, status epilepticus, and end-of-life care.

©1997-2008 The Neurological Institute of New York • At Columbia University Medical Center
Updated March 13, 2008Comments
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