MEGALOBLASTIC ANEMIA

MARROW FAILURE

MEGALOBLASTIC ANEMIA

MEGALOBLASTIC ANEMIA

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FOLIC ACID

FOLIC ACID

FOLIC ACIDOne Carbon Fragment Forms

FOLATE ABSORPTION

THYMIDILATE SYNTHESIS

FOLATE DEFICIENCYCauses

FOLATE DEFICIENCYManifestations

COBALAMIN (Vitamin B12)Functions

COBALAMINStructure

COBALAMIN REACTIONS

GI ABSORPTION OF COBALAMIN

COBALAMIN DEFICIENCYCauses

PERNICIOUS ANEMIA

COBALAMIN DEFICIENCYPeripheral Folate Depletion

COBALAMIN DEFICIENCYPeripheral Manifestations

COBALAMIN DEFICIENCYManifestations-Central

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COBALAMIN DEFICIENCYUsual Sequence of Events

FOLATE/COBALAMINProperties

MEGALOBLASTIC ANEMIA Diagnosis /Therapy

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MEGALOBLASTIC ANEMIAResponse to Therapy

SCHILLING TEST

MEGALOBLASTIC ANEMIASSummary