Publications for Gary A. Heiman, Ph.D.
Bressman SB, Heiman GA, Nygaard T, Ozelius L, Hunt A, Brin MF, Gordon M, Moskowitz CB, DeLeon D, Burke R, Fahn S, Risch N, Breakefield XO, & Kramer P. A study of idiopathic torsion dystonia in a non-Jewish family: Evidence for genetic heterogeneity. Neurology 44: 283—287, February, 1994.
Kramer P, Heiman GA, Gasser T, Ozelius L, DeLeon D, Brin MF, Burke R, Hewett J, Hunt A, Moskowitz CB, Nygaard T, Wilhelmsen K, Fahn S, Breakefield XO, Risch NJ, & Bressman SB. The DYT1 gene on 9q34 is responsible for most cases of early limb-onset idiopathic torsion dystonia in non-Jews. Am J Hum Genet 55: 468—475, September, 1994.
Bressman SB, Hunt A, Heiman GA, Brin MF, Burke R, Fahn S, Trugman J, DeLeon D, Kramer P, Wilhelmsen K, & Nygaard T. Exclusion of the DYT1 locus in a non-Jewish family with early-onset Dystonia. Mov Disord, 9: 626—632, 1994.
Heiman GA, Hodge SE, Wickramaratne P, & Hsu H. Age-at-interview bias in anticipation studies: computer simulations and an example with panic disorder. Psychiat Genet 6: 61—66, 1996.
Bressman SB, Warner TT, Almasy L, Uitti RJ, Greene PE, Heiman GA, Raymond D, Ford B, de Leon D, Fahn S, Kramer P, Risch NJ, Maraganore DM, Nygaard TG, & Harding AE. Exclusion of the DYT1 locus in familial torticollis. Ann Neurol 40: 681—684, 1996.
Almasy L, Bressman SB, Raymond D, Kramer P, Greene PE, Heiman GA, Ford B, Yount BA, de Leon D, Chouinard S, Saunders-Pullman R, Brin MF, Kapoor RP, Jones AC, Shen H, Fahn S, Risch NJ, & Nygaard TG. Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Ann Neurol 42: 670—673, 1997.
Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, de Jesus GM, Rassnick H, Preud'homme-Rivelli X, Austin T, Cunjak J, Mick S, Fine LD, Woodley KA, Das K, Maier W, Adams PB, Freimer NB, Klein DF, and Gilliam TC. Results of a genome-wide genetic screen for panic disorder. Am J Med Genet (Neuropsychiat Genet) 81: 139-147, 1998.
Hamilton SP, Heiman GA, Haghigi F, Mick S, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA. Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder. Psychiat Genet 9: 1—6, 1999.
Nygaard TG, Raymond D, Chen C, Nishino I, Greene PE, Jennings D, Heiman GA, Klein C, Saunders-Pullman RJ, Kramer P, Ozelius LJ, and Bressman SB. Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. Ann Neurol 46 (5):794—798, 1999.
Weissman MM, Fyer AJ, Haghigi F, Heiman GA, Deng Z, Hen R, Hodge SE, and Knowles JA. A potential panic disorder syndrome: clinical and genetic linkage evidence. Am J Med Genet (Neuropsychiatr Genet) 96:24—35, 2000.
Hamilton SP, Haghigi F, Heiman GA, Klein DF, Hodge SE, Fyer AJ, Weissman MM, and Knowles JA. Investigation of Dopamine Receptor (DRD4) and Dopamine Transporter (DAT) Polymorphisms for Genetic Linkage or Association to Panic Disorder. Am J Med Genet (Neuropsychiatr Genet) 96:324—330, 2000.
Hamilton SP, Slager SL, Heiman GA, Haghighi F, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA. No genetic linkage or association between a functional promoter polymorphism in the Monoamine Oxidase-A gene and panic disorder. Mol Psychiatry 5:465—466, 2000.
Hamilton SP, Slager SL, Helleby L, Heiman GA, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA. No association or linkage between polymorphisms in the genes encoding Cholecystokinin and the Cholecystokinin B receptor and panic disorder. Mol Psychiatry 6:59—65, 2001.
Hamilton SP, Slager SL, Heiman GA, Deng Z, Haghighi F, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA. Evidence for susceptibility locus for panic disorder near the catechol-o-methyltransferase gene on chromosome 22. Biol Psychiatry 51: 591—601, 2002.
Saunders-Pullman R, Shriberg J, Heiman GA, Raymond R, Wendt K, Kramer P, Schilling K, Kurlan R, Klein C, Ozelius LJ, Risch NJ, PhD and Bressman SB. The spectrum of myoclonus dystonia: Possible association with OCD and alcohol dependence. Neurology 58: 242-245, 2002.
Ahsan H, Hodge SE, Heiman GA, Begg MD and Susser ES. Relative risk for genetic associations: the case-parent triad as a variant of case-cohort design. Int. J. Epidemiol. 31(3): 669-678, 2002.
Hamilton SP, Fyer AJ, Durner, M, Heiman GA, de Leon AB, Hodge SE, Knowles JA, and Weissman MM. Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q. Proc Natl Acad Sci 100(5): 2550-2555, 2003.
Weissman MM, Gross R, Fyer, AF, Heiman GA, Gameroff MJ, Hodge SE, Kaufman D, Kaplan SA and Wickramaratne P. Interstitial cystitis and panic disorder: A potential genetic syndrome. Arch Gen Psych 61:273 - 279, 2004.
Hamilton SP, Slager SL, Mayo D, Heiman GA, Klein DF, Hodge SE, Fyer AJ, Weissman MM, and Knowles JA. Investigation of polymorphisms in the CREM gene in panic disorder. Am J Med Genet (Neuropsychiatr Genet) 126B:111-115, 2004.
Heiman GA, Ottman R, Saunders-Pullman R, Ozelius LJ, Risch NJ, PhD and Bressman SB. Increased risk for recurrent major depression in DYT1 dystonia mutation carriers. Neurology 63(4): 631-637, 2004.
Hamilton SP, Slager SL, de Leon AB, Heiman GA, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA. Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor (ADORA2A) and panic disorder. Neuropsychopharmacology 29(3):558-565, 2004.
Heiman GA, Hodge SE, Gorroochurn P, Zhang J, and Greenberg DA. Effect of population stratification on case-control association studies. I: elevation in false positive rates and comparison to confounding risk ratios (a simulation study). Human Heredity 58:30-39, 2004.
Gorroochurn P, Hodge SE, Heiman GA, and Greenberg DA. Effect of population stratification on case-control association studies. II: false-positive rates and their limiting behavior as number of subpopulations increases. Human Heredity 58:40-48, 2004.
Tsai WY, Heiman GA, and Hodge SE. Simple Tests for age-at-onset anticipation: Application to panic disorder. Genetic Epidemiology 28:256-260 2005.
