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The Use of Decision Analysis in Treatment
Planning for Patients with Periodontal Disease
Rakhi Sinha, BS* ; Ira B. Lamster, DDS, MMSc**
ABSTRACT
The past several years have seen dramatic changes in the diagnosis and treatment
of periodontal disease. Research has focused on the development of new methods
to aid the clinician in the evaluation and treatment of patients. This research
has caused a reassessment of how treatment decisions are made for the patient
with periodontal disease. The purpose of this article is to discuss the
use of decision trees for the examination and treatment of periodontal patients.
Decision trees can allow clinicians to consider all options that are available
when formulating a treatment plan, and modify approaches to therapy as treatment
progresses. (Col Dent Rev 2:35, 1997)
INTRODUCTION
Studies during the past ten years have suggested that many long held
beliefs concerning the diagnosis of periodontal disease need to be re-examined.
First, our understanding of the natural history of these common disorders
has been modified based on longitudinal clinical trials. The progression
of periodontal disease had been considered to be slow and continuous throughout
the adult life of affected individuals. We now understand that the periodontal
diseases are similar to other chronic disorders in that they are characterized
by periods of exacerbation (brief) and remission (longer).6
At the same time, our approach to the diagnosis of these diseases is
changing. For many years, diagnosis has relied on clinical parameters such
as probing depth and radiographic evidence of existing alveolar bone loss.
These techniques are recognized as quite useful in evaluating past disease,
but offer little insight in evaluating patient's risk of experiencing active
disease in the near term. For this reason, there is considerable interest
in developing new approaches for diagnosis of
patients. These new diagnostic tests seek to identify the "biochemical"
lesion prior to the progression to the clinical lesion. Therefore, the dentist/periodontist
of the future will rely on both traditional and diagnostic methods to evaluate
patients. The use of these diagnostic methods involves the identification
of microbial challenge and mediators of the host response ( Figure 1).
Research aimed towards new diagnostic tests for periodontal disease has
focused on identification of bacterial DNA1, cell surface antigens7 as well
as the presence of specific organisms as identified by culture.5 Measurement
of the host's immune and inflammatory response is usually performed by analysis
of gingival crevicular fluid (GCF), serum, or saliva.4 These tests, perhaps
used in combination, appear to offer a sensitive method to determine the
risk for active periodontal disease.3 As a result, there are important therapeutic
implications of this new understanding about the natural history of periodontal
disease. Specifically, it is critical to identify patients at risk for periods
of active disease.
DECISION TREES
With this new appreciation of the natural history of periodontal disease,
and the options available to the clinician regarding periodontal diagnosis,
it is reasonable to suggest that care for the periodontal patient will improve
with the use of clinical decision analysis. The practical application of
decision analysis is the decision tree. This is a schematic diagram of potential
pathways taken in the course of diagnosis and treatment. It is a visual
representation of the action being considered by the clinician. Decision
trees generally read from left to right. The point from which the tree originates
is called the decision node.2 The initial choices that are available to
the clinician are the first branches that emanate from the decision node.
These branches lead to other choices along a particular pathway.
This type of analysis has been used in medicine for many years, and now
should be applied to dental patients. Figure 2 is a decision tree that provides
options in the treatment of patients with mild, moderate, or advanced periodontitis.
In addition, probabilities can be included in a decision tree. These probabilities
allow clinicians to assess the chance of success (or failure) and the risk
associated with a particular procedure. These values allow informed decisions
to be made.

DISCUSSION
Periodontal disease is a multifactorial disorder affecting the supporting
structures of teeth. It is the complex nature of this chronic disorder that
requires a clinician to thoroughly investigate each possible therapeutic
option to fit the patient's particular need. Patients with mild disease
can be evaluated after initial therapy in order to assess the response to
therapy. Assuming an appropriate response, the clinician would then decide
upon the recall interval. Patients with moderate disease are evaluated after
initial therapy and the clinician decides whether to continue with nonsurgical
procedures, or if the patient would benefit from anti-infective therapy
or periodontal surgery. With the increase in severity of the disease, more
options are now available to the clinician. New diagnostic methods would
be most beneficial for the patient with advanced disease. The development
of decision trees may be helpful for considering options available in the
diagnostic and therapeutic phases of periodontal therapy. The "therapy"
decision tree would be modified based on findings from the "diagnostic"
decision tree. While no specific therapy would be dictated by any diagnostic
finding, the identification of low, moderate, or high risk patients would
trigger different treatments. These treatments would be aimed at halting
progressive disease, and the intensity of treatment regimen would depend
on the degree of risk.
CONCLUSION
It is evident that the use of decision analysis can help quantitate therapeutic
options. Decision trees offer the clinician a logical approach to tailoring
the diagnostic and treatment needs for individual patients.
REFERENCES
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bacteria in clinical samples. In: Hamada S, Holt SC, McGhee JR, editors.
Periodontal diseases: pathogens and host immune responses. Tokyo: Quintessence
367-377.
2. Kramer MS (1988). Clinical Epidemiology and Biostatistics. Springer-Verlag,
Berlin.
3. Lamster IB, Celenti RS, Jans HH, Fine JB, Grbic JT (1993). Current status
of tests for periodontal disease. Advances in Dental Research 7:
182-190.
4. Lamster IB, Grbic JT (1995).Diagnosis of periodontal disease based on
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5. Listgarten MA (1992). Microbiological testing in the diagnosis of periodontal
disease. Journal of Periodontology 63: 332-337.
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Boyer BP, Mayer J, Mangan T, Norkus N, Zambon JJ, Genco RJ (1996). Analytical
performance of an immunologic-based periodontal bacterial test for simultaneous
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